ncRNA name | E6/E7 siRNA |
ncRNA Category | siRNA |
Disease name | uveal melanoma (UM) |
Species | Homo sapiens |
Tissues/Cell_line | human UM cell lines OCM1, OM431, VUP and SP6.5 |
Methods | PCR, DNA CHIP, Western blot, siRNA transfection, MTT assay, flow cytometry |
Expression pattern | associated |
Functional description | Down regulation of HPV 18E6/E7 led to growth inhibition and cell cycle block in VUP cells by activation of the p53 and Rb pathways. |
PubMed ID | 23494180 |
Year | 2013 |
Title | Cell growth inhibition in HPV 18 positive uveal melanoma cells by E6/E7 siRNA. |
Drug-related ncRNA | NO |
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